January 12, 2015
Corresponding author: Leroy Hood lee.hood@systemsbiology.org
Institute for Systems Biology, 401 Terry Avenue North, Seattle 98109, WA, USA
BMC Medicine 2015, 13:4 doi:10.1186/s12916-014-0238-7
More about author:
Lee Hood Group, Institute for Systems Biology
Abstract
The Hundred Person Wellness Project (HPWP) is a 10-month pilot study of 100 ‘well’ individuals where integrated data from whole-genome sequencing, gut microbiome, clinical laboratory tests and quantified self measures from each individual are used to provide actionable results for health coaching with the goal of optimizing wellness and minimizing disease. In a commentary in BMC Medicine, Diamandis argues that HPWP and similar projects will likely result in ‘unnecessary and potential harmful over-testing’. We argue that this new approach will ultimately lead to lower costs, better healthcare, innovation and economic growth. The central points of the HPWP are: 1) it is focused on optimizing wellness through longitudinal data collection, integration and mining of individual data clouds, enabling development of predictive models of wellness and disease that will reveal actionable possibilities; and 2) by extending this study to 100,000 well people, we will establish multiparameter, quantifiable wellness metrics and identify markers for wellness to early disease transitions for most common diseases, which will ultimately allow earlier disease intervention, eventually transitioning the individual early on from a disease back to a wellness trajectory.
The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1741-7015/13/4
image source: The Hundred Person Wellness Project will include around-the-clock monitoring of subjects, news.com.au
