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Magnetic nanoparticle drug delivery systems for targeting tumor

Corresponding Author:  Vicky V. Mody vmody@southuniversity.edu

Department of Pharmaceutical Sciences, College of Pharmacy, South University School of Pharmacy, 709 Mall Blvd, Savannah, GA 31406, USA

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Applied Nanoscience, Volume 4, Issue 4, pp 385-392,



Abstract
Tumor hypoxia, or low oxygen concentration, is a result of disordered vasculature that lead to distinctive hypoxic microenvironments not found in normal tissues. Many traditional anti-cancer agents are not able to penetrate into these hypoxic zones, whereas, conventional cancer therapies that work by blocking cell division are not effective to treat tumors within hypoxic zones. Under these circumstances the use of magnetic nanoparticles as a drug delivering agent system under the influence of external magnetic field has received much attention, based on their simplicity, ease of preparation, and ability to tailor their properties for specific biological applications. Hence in this review article we have reviewed current magnetic drug delivery systems, along with their application and clinical status in the field of magnetic drug delivery.


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⓿ The electronic version of this article is the complete one and can be found online at: http://link.springer.com/article/10.1007/s13204-013-0216-y/fulltext.html

Sustainability in the wine industry: key questions and research trends

Corresponding author: Cristina Santini santini.cristina@gmail.com

Faculty of Agriculture, Università San Raffaele, Via Val Cannuta 247, Roma, Italy

Agricultural and Food Economics 2013, 1:9  doi:10.1186/2193-7532-1-9





Abstract
Sustainability is playing a key role in the wine industry as shown by the attention paid at several levels by the academia, institutions and associations. Nevertheless, the principle itself of sustainability opens a wide debate and it significantly affects firms in all their activities.


Using a systematic literature review, this paper wants to highlight some of the questions that academics must face when they approach the issue of sustainability with a specific focus on the wine industry. In particular the paper aims to: highlight where research is going and what has already been done; define the contribution of background research in explaining the determinants of sustainable orientation in the wine industry; and understand the role of research (and academics’ social responsibility) for the diffusion of a sustainable orientation within the wine industry. The purpose of this paper is to provide a detailed overview of the main research contributions to the issue of sustainability in the wine industry.


The electronic version of this article is the complete one and can be found online at: http://www.agrifoodecon.com/content/1/1/9



Image source: alum.mit.edu

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