Next Creation Changing Your Future?

Edited by: Prof Yi-Ching Wang 

More about Prof. Yi-Ching Wang

Transcription is accomplished in an efficient and faithful manner by nuclear RNA polymerases, transcription factors, chromatin regulators, and signaling pathways. Recently, various detection techniques and genome-wide profiling have shown that transcriptional deregulation gives rise to several significant human diseases including various cancers, neuron disorders, psychosis, and cardiovascular diseases. In this special collection of reviews we hope to provide readers with insightful information on the nature of transcriptional regulation and its dysregulation in diseases, focusing on ribosomal gene transcription, RNA editing, non-histone methylation and DNA methylation regulations.

Whole collection at http://www.cellandbioscience.com/series/transcriptional_reg_dis

Review    

Dysregulated transcriptional and post-translational control of DNA methyltrasferases in cancer

Ruo-Kai Lin, Yi-Ching Wang

Cell & Bioscience 2014, 4:46 (19 August 2014)

Review   

Epigenetic regulation in cancer progression

Eva Baxter, Karolina Windloch, Frank Gannon, Jason S Lee

Cell & Bioscience 2014, 4:45 (19 August 2014)

Review    

Functional Impact of RNA editing and ADARs on regulation of gene expression: perspectives from deep sequencing studies

Hsuan Liu, Chung-Pei Ma, Yi-Tung Chen, Scott C Schuyler, Kai-Ping Chang, Bertrand Chin-Ming Tan

Cell & Bioscience 2014, 4:44 (19 August 2014)

Review    

Perturbations at the ribosomal genes loci are at the centre of cellular dysfunction and human disease

Jeannine Diesch, Ross D Hannan, Elaine Sanij

Cell & Bioscience 2014, 4:43 (19 August 2014)

Editorial    

Thematic series: Transcriptional regulation and disease

Yi-Ching Wang

Cell & Bioscience 2014, 4:42 (19 August 2014)



image source: Transcription Factor And Dna Molecules